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. 2022 Mar 14;140:105725. doi: 10.1016/j.psyneuen.2022.105725

Table 2.

Clinical criteria for allostatic overload (A through B are required) (from Fava et al., 2019).

Criterion A The presence of a current identifiable source of distress in the form of recent life events and/or chronic stress; the stressor is judged to tax or exceed the individual coping skills when its full nature and circumstances are evaluated
Criterion B The stressor is associated with one or more of the following features, which have occurred within 6 months after the onset of the stressor:
  • 1.

    At least two of the following symptoms: difficulty falling asleep, restless sleep, early morning awakening, lack of energy, dizziness, generalized anxiety, irritability, sadness, demoralization

  • 2.

    Significant impairment in social or occupational functioning

  • 3.

    Significant impairment in environmental mastery (feeling overwhelmed by demands of everyday life)