Table 1.

Sex Differences in PAD Presentation and Management

	Sex Differences in PAD
Clinical Presentation
Symptoms	Women more likely to have no or atypical leg symptoms
Examination	Women more likely to have greater functional decline and reduced walking parameters and quality of life
Diagnostics	Women more likely to present with multilevel disease
Management
Hyperlipidemia	Women less often treated with lipid-lowering therapies, and female sex associated with lower odds of achieving target LDL-C
Hypertension	Men more likely to be treated with an ACE inhibitor and to achieve target blood pressure
Antithrombotic therapy	Lower use of antiplatelet therapy consistently observed among women
Supervised exercise therapy (SET)	Small studies suggest less response to SET in women than men, though data are sparse
Revascularization	Older data suggest lower use of revascularization in women, but more recent data show similar use between women and men