Table 1.
Analysis of frequency, length, and quantity of the menstrual cycle after the administration of the first dose of vaccine, stratified for the type of vaccine and the phase of the menstrual cycle during which the vaccine was administered
| Type of vaccine | Phase of the menstrual cycle during administration | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Vaxzevria (AstraZeneca) | Comirnaty (Pfizer-BioNtech) | Spikevax (Moderna) | Janssen (Johnson & Johnson) | Menstruation | Early-mid follicular phase | Late follicular phase | Early-mid luteal phase | Late luteal phase | Unknown | |
| Frequency | ||||||||||
| I did not notice any variation of the frequency | 3 (33.3%) | 58 (42.9%) | 10 (52.6%) | 2 (66.7%) | 11 (43.5%) | 9 (34.6%) | 13 (36.1%) | 4 (21.1%) | 9 (47.4%) | 27 (65.9%) |
| I did not have menstrual cycle | 1 (11.1%) | 6 (4.5%) | 1 (5.3%) | 0 | 1 (4.3%) | 1 (3.8%) | 0 | 3 (15.8%) | 1 (5.3%) | 2 (4.9%) |
| Menstruation arrived 1–5 days earlier than expected | 3 (33.3%) | 24 (18%) | 4 (21.1%) | 1 (33.3%) | 5 (21.7%) | 7 (26.9%) | 7 (19.4%) | 3 (15.8%) | 4 (21.1%) | 6 (14.6%) |
| Menstruation arrived 5–10 days earlier than expected | 1 (11.1%) | 9 (6.8%) | 2 (10.5%) | 0 | 1 (4.3%) | 2 (7.7%) | 3 (8.3%) | 3 (15.8%) | 1 (5.3%) | 2 (4.9%) |
| Menstruation arrived more than 10 days earlier than expected | 1 (11.1%) | 11 (8.3%) | 1 (5.3%) | 0 | 2 (8.7%) | 4 (15.4%) | 4 (11.1%) | 1 (5.3%) | 1 (5.3%) | 1 (2.4%) |
| Menstruation arrived 1–5 days later than expected | 0 | 12 (9%) | 1 (5.3%) | 0 | 0 | 2 (7.7%) | 4 (11.1%) | 3 (15.8%) | 3 (15.8%) | 1 (2.4%) |
| Menstruation arrived 5–10 days later than expected | 0 | 7 (5.3%) | 0 | 0 | 1 (4.3%) | 0 | 4 (11.1%) | 2 (10.5%) | 0 | 0 |
| Menstruation arrived more than 10 days later than expected | 0 | 6 (4.3%) | 0 | 0 | 2 (8.7%) | 1 (3.8%) | 1 (2.8%) | 0 | 0 | 2 (4.9%) |
| Totals | 9 (100%) | 133 (100%) | 19 (100%) | 3 (100%) | 23 (100%) | 26 (100%) | 36 (100%) | 19 (100%) | 19 (100%) | 41 (100%) |
| Length | ||||||||||
| I did not notice any variation of the length | 4 (44.4%) | 78 (58.6%) | 9 (47.4%) | 1 (33.3%) | 13 (56.5%) | 15 (57.7%) | 21 (58.3%) | 6 (31.6%) | 11 (57.9%) | 26 (63.4%) |
| I had spotting | 2 (22.2%) | 12 (9%) | 0 | 0 | 2 (8.7%) | 2 (7.7%) | 2 (5.6%) | 3 (15.8%) | 1 (5.3%) | 4 (9.8%) |
| Menstruation lasted more than 7 days | 2 (22.2%) | 21 (15.8%) | 3 (15.8%) | 2 (66.7%) | 4 (17.4%) | 5 (19.2%) | 6 (16.7%) | 7 (36.8%) | 3 (15.8%) | 3 (7.3%) |
| Menstruation lasted less than 3 days | 1 (11.1%) | 22 (16.5%) | 7 (36.8%) | 0 | 4 (17.4%) | 4 (15.4%) | 7 (19.4%) | 3 (15.8%) | 4 (21.1%) | 8 (19.5%) |
| Totals | 9 (100%) | 133 (100%) | 19 (100%) | 3 (100%) | 23 (100%) | 26 (100%) | 36 (100%) | 19 (100%) | 19 (100%) | 41 (100%) |
| Quantity | ||||||||||
| I did not notice any variation of the quantity | 3 (33.3%) | 71 (52.6%) | 9 (47.4%) | 1 (33.3%) | 12 (52.2%) | 12 (46.2%) | 20 (55.6%) | 5 (26.3%) | 10 (52.6%) | 25 (58.5%) |
| Menstruation was heavier than usual | 5 (55.6%) | 33 (24.8%) | 3 (15.8%) | 2 (66.7%) | 6 (26.1%) | 11 (42.3%) | 8 (22.2%) | 11 (57.9%) | 3 (15.8%) | 4 (9.8%) |
| Menstruation was less heavy than usual | 1 (11.1%) | 29 (21.8%) | 7 (36.8%) | 0 | 5 (21.7%) | 3 (11.5%) | 8 (22.2%) | 3 (15.8%) | 6 (31.6%) | 12 (29.3%) |
| Totals | 9 (100%) | 133 (100%) | 19 (100%) | 3 (100%) | 23 (100%) | 26 (100%) | 36 (100%) | 19 (100%) | 19 (100%) | 41 (100%) |