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. Author manuscript; available in PMC: 2022 Nov 1.
Published in final edited form as: Am J Obstet Gynecol MFM. 2021 Aug 18;3(6):100466. doi: 10.1016/j.ajogmf.2021.100466

Table 4:

Cell-free DNA test characteristics by maternal autoimmune disease and immunomodulator therapy status

AID (−)
Immunomodulator Therapy
(n=25)		 AID (+)
Immunomodulator Therapy
(n=18)		 No AID
(n=1402)		 p-value
Fetal fraction (%) 9.8 ± 5.7 9.6 ± 5.5 11.9 ± 5.0 0.02
Indeterminate rate 5 (20.0) 2 (11.1) 49 (3.5) 0.001
Total cfDNA (pg/uL) 96.4 (73.5–134.0) 94.8 (63.1–163.0) 83.9 (59.0–117.0) 0.08

Data are mean ±SD, N (%), median (interquartile range)

AID, autoimmune disease; cfDNA, cell-free DNA