TABLE 4.
Transfer Completion Rate∗ by Transfer Component
| Variable | Transfer Completion Rate (Unweighted) | F or t Statistic and Corresponding P |
| Setting | ||
| Inpatient | 125/138 (90.6%) | t = -1.41 |
| Outpatient | 154/163 (94.5%) | P = 0.18 |
| Pretransfer METH dose† | ||
| <40 mg | 108/110 (98.2%) | |
| 40–60 mg | 86/93 (92.5%) | F = 4.23 |
| > 60 mg | 66/81 (81.5%) | P = 0.03 |
| Minimum wait time before initial BUP dose | ||
| ≤ 24 h‡ | 121/129 (93.8%) | t = 1.12 |
| > 24 h | 176/194 (90.7%) | P = 0.28 |
| Degree of withdrawal at initial BUP dose | ||
| Mild | 81/86 (94.2%) | t = 0.44 |
| Moderate | 107/121 (88.4%) | P = 0.66 |
| BUP product | ||
| BUP monotherapy | 211/230 (91.7%) | t = 0.09 |
| BUP + NLX | 90/97 (92.8%) | P = 0.93 |
| Initial first-day BUP strategy | ||
| Fixed dose | 202/220 (91.8%) | t = -0.17 |
| Flexible dose | 105/114 (92.1%) | P = 0.87 |
| Total first-day BUP strategy‡ | ||
| Single dose | 105/111 (94.6%) | F = 0.49 |
| Split dose | 114/128 (89.1%) | P = 0.62 |
| Mixed or flexible strategy | 78/84 (92.9%) | |
| Overall | 307/334 (91.9%) | NA |
∗
Defined as achieving and maintaining a stable dose of BUP, unless defined otherwise by individual study.
†
Transfer completion rates were identical for starting METH dose and METH dose averaged over final 5 days.
‡
Does not include the study that administered a 35 μg/hr BUP patch at 12 hours after last METH dose.
BUP indicates buprenorphine; METH, methadone; NA, not applicable; NLX, naloxone.