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. 2021 Nov 8;15(3):e009195. doi: 10.1161/CIRCHEARTFAILURE.121.009195

Figure 6.

Figure 6.

TA1 at 60 nmol/L achieves similar rate-pressure product (RPP) at higher developed pressure (DevP), wall stress and lower heart rate (HR), and left ventricular end diastolic pressure (LVEDP) compared with 120 nmol/L dobutamine (Dob), with neutral effect on ATP synthesis rate.

A through E, During magnetization transfer, 60 nmol/L TA1 achieved higher DevP and wall stress (A and C), lower LVEDP (D) and HR (B), and similar RPP (E) compared with 120 nmol/L Dob. ATP synthesis rate was similar between the groups. F, n=9 (in 60 nmol/L TA1 group) and 10 (in 120 nmol/L Dob group). Data shown are mean±SEM. P values were obtained by unpaired t tests. *P<0.05 and **P<0.01, respectively. w.w. indicates wet weight.