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. Author manuscript; available in PMC: 2022 Mar 14.
Published in final edited form as: Exp Gerontol. 2022 Jan 13;159:111669. doi: 10.1016/j.exger.2021.111669

Fig. 1.

Fig. 1.

Calorie restriction (CR) and 17α-E2 differentially modulate body mass in female mice. (A) Body mass and (B) % change in body mass in female control (CTL) mice and those treated with 17α-E2 or CR regimens (10% or 30%) for 18 weeks starting at 12 weeks of age. All data are presented as mean ± SEM and were analyzed by repeated measures ANOVA or one-way ANOVA where appropriate. Different letters indicate statistical differences (p < 0.05) between groups (n = 18/group).