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. Author manuscript; available in PMC: 2022 Mar 14.
Published in final edited form as: Exp Gerontol. 2022 Jan 13;159:111669. doi: 10.1016/j.exger.2021.111669

Fig. 2.

Fig. 2.

Both mild (10%) and moderate (30%) calorie restriction (CR) regimens positively affect ovarian reserve. Number of primordial (A), transition (B), primary (C), secondary (D), tertiary (E) and total follicles (F) per section area (mm2) from female control (CTL) mice and those treated with 17α-E2 or CR regimens (10% or 30%) for 24 weeks starting at 12 weeks of age (n = 9 sections/mouse; 5 mice/group). All data are presented as mean ± SEM and were analyzed using the mixed procedure test in SAS. Different letters indicate statistical differences (p < 0.05) between groups.