. Author manuscript; available in PMC: 2023 Mar 1.

Published in final edited form as: Acta Ophthalmol. 2021 Aug 6;100(2):e377–e385. doi: 10.1111/aos.14982

Table 3:

Choroid Layer optical coherence tomography angiography (OCTA) Vascular Markers. OAG: open-angle glaucoma; ONH: optic nerve head.

Author (year)	Subjects	OCTA Scan	Results	P-value
Tepelus et al. (2019)	26 low tension glaucoma (LTG) patients 22 age-matched healthy subjects	6 × 6 mm² macular layers	LTG group had lower perfusion density of the choriocapillaris compared with normal controls	P<0.001
Tepelus et al. (2019)		6 × 6 mm² macular layers	LTG group showed reductions in vessel length density compared with controls for the superficial vascular plexus and optic nerve head + peripapillary area	P=0.03 for both
Park et al. (2018)	82 OAG with disc hemorrhage 68 OAG without disc hemorrhage	4.5 × 4.5 mm ONH	Choroid microvascular dropout was greater in patients with glaucoma and previous disc hemorrhage than glaucoma patients without previous disc hemorrhage	P=0.025
			Within the Disc-Hemorrhage group, progressive glaucoma patients (as defined by OCTA) had significantly greater choroid microvascular dropout compared to stable patients (77.3% vs. 10.5%)	P<0.001
			Within the non-Disc Hemorrhage group, progressive glaucoma patients had significantly greater choroid microvascular dropout compared to stable patients (50% vs. 23.1%)	P<0.001