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. 2022 Feb 28;14:834114. doi: 10.3389/fnagi.2022.834114

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Copyright © 2022 Zhang, Liang, Yang, Ren, Cheng, Wu, He and Yin.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Comparison of systemic inflammatory biomarkers and serum SOD levels between CR and nCR. (A–C) Comparison of systemic inflammation biomarkers. Compared to the CR group, ESR, CRP, and IL-6 (A–C) increased in the nCR group at baseline (T0), especially ESR levels, which were consistently (T0 and T1) higher in the nCR group (A). (D) Comparison of serum SOD levels. SOD was continuously lower in the nCR group, especially at baseline. T0 means baseline, T1 means 3-month follow-up. ESR, IL-6, CRP, and SOD at baseline and 3 months were compared between two groups by Mann-Whitney U test. *P < 0.05, ^**P < 0.01.