TABLE 1.
Baseline characteristics of the recruited patients.
| Characteristics* | CI-E | nCI-E | P |
| No. of subjects | 105 (56.1) | 82 (43.9) | |
| Demographics | |||
| Age, y | 59 (13) | 54 (16) | 0.001 |
| Female | 27 (25.7) | 12 (14.6) | 0.064 |
| Education, y | 7 (3) | 8 (2) | 0.000 |
| Cigarette smoking | 55 (52.4) | 47 (57.3) | 0.501 |
| Alcohol drinking | 23 (21.9) | 29 (35.4) | 0.041 |
| Medical histories | |||
| History of hypertension | 69 (65.7) | 58 (70.7) | 0.466 |
| History of hyperlipidemia | 38 (36.2) | 29 (35.4) | 0.907 |
| History of diabetes | 43 (41.0) | 23 (28.0) | 0.067 |
| History of stroke | 55 (52.4) | 47 (46.1) | 0.501 |
| Clinical features | |||
| BMI, kg/m2 | 24.2 (4.2) | 24.3 (4.2) | 0.722 |
| Baseline NIHSS score | 2 (4) | 2 (2) | 0.859 |
| Baseline BI | 80 (35) | 85 (35) | 0.517 |
| Infarcted location (Cortical infarct) | 33 (31.4) | 29 (35.4) | 0.570 |
| Stroke causes (LAA) | 65 (61.9) | 43 (52.4) | 0.193 |
| Baseline laboratory findings | |||
| WBC, ×109/L | 7.6 (2.8) | 7.8 (3.1) | 0.799 |
| NEU, ×109/L | 5.0 (2.2) | 4.6 (2.8) | 0.459 |
| LYM, ×109/L | 2.0 (0.9) | 1.9 (1.2) | 0.909 |
| ESR, mm/h | 10 (12) | 6 (9) | 0.000 |
| IL-6, pg/mL | 3.54 (3.91) | 2.65 (2.63) | 0.001 |
| CRP, mg/L | 1.37 (2.48) | 0.90 (2.50) | 0.044 |
| Cognitive scores within 2 weeks | |||
| MMSE | 24 (5) | 28 (2) | <0.001 |
| MoCA | 16 (7) | 24 (3) | <0.001 |
*Continuous variables are expressed as median (IQR). Categorical variables are expressed as frequencies (percentages).
CI-E, early cognitive impairment after stroke; nCI-E, non-early cognitive impairment after stroke; LAA, large-artery atherosclerosis; WBC, white blood cells count; NEU, neutrophil count; LYM, lymphocyte count; ESR, erythrocyte sedimentation rate; CRP, C-reactive protein; IL-6, interleukin-6.