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. 2022 Mar 8;14(1):2046246. doi: 10.1080/19490976.2022.2046246

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© 2022 The Author(s). Published with license by Taylor & Francis Group, LLC.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 3. — Lactobacillus was positively associated with antitumor immune response. (a) Differential relative abundance of taxa at the genus level between the FMT-CRC and FMT-HD group (n = 7). (b) Relationship of genera with different abundances. Lactobacillus was negatively correlated with almost all other genera with different relative abundances. (c) Gut microbial signature associated with anti-PD-1 outcomes in mice. (d) ROC analysis of the power of four genera as predictive of anti-PD-1 outcomes. (e) The ranking of four genera by their importance to the gut microbial community. (f) Kaplan-Meier survival analysis based on the abundance of Lactobacillus in the tumor-bearing mice (n = 14). MDA, mean decrease in accuracy.