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. 2021 Oct 6;18(1):1981086. doi: 10.1080/21645515.2021.1981086

Table 2.

Side effect after receiving vaccines related to the dose

  First dose N (%) N = 1086 Second dose N(%) N = 299 P value
Local symptoms
Injection site pain
Swelling and redness of injection site
851 (78.4)
177 (16.3)
200 (66.8)
45 (15.0)
0.004
0.216
Bone and muscle pain 408 (37.6) 85 (28.4) <0.001
Flu like symptoms
Fever
Headache
Chills
Sore throat
Fatigue
Cough
Runny nose
Loss of taste
Loss of smell
300 (27.6)
359 (33.1)
351 (32.3)
90 (8.3)
563 (51.8)
91 (8.4)
76 (7.0)
14 (1.3)
16 (1.5)
57 (19.1)
59 (19.7)
69 (23.1)
18 (6.0)
121 (40.4)
10 (3.3)
14 (4.6)
2 (0.7)
3 (1.0)
<0.001
<0.001
<0.001
0.031
<0.001
0.048
0.115
0.264
0.428
GI side effect
Nausea
Diarrhea
Vomiting
Loss of appetite
Abdominal pain
Constipation
164 (15.1)
70 (6.4)
30 (2.8)
102 (9.4)
65 (6.0)
7 (0.6)
23 (7.7)
13 (4.3)
8(2.7)
19 (6.3)
7 (2.3)
2 (0.7)
<0.001
0.022
0.003
<0.001
<0.001
0.431
Psychological side effect
Sleep disturbance
Anxiety and stress
Depression
110 (10.1)
68 (6.3)
48(4.4)
22 (6.7)
8 (2.4)
6 (1.8)
<0.001
0.003
0.007
Irregular menses (Females) 17 (1.6) 4 (1.3) 0.861
Decreased libido 14 (1.3) 5 (1.6) 0.264
Lymph node enlargement and swelling 12 (1.1) 4 (1.3) 0.044
Eye symptoms
Blurred vision
40 (3.7) 8 (2.7) 0.011
Skin itching
Acne
Sweating
29 (2.7)
22 (2.0)
76 (7.0)
6 (2.0)
5 (1.6)
11 (3.7)
0.209
0.978
0.001
Increase urination
Change urine color
16 (1.5)
11 (1.0)
2 (0.7)
2 (0.7)
0.428
0.985
Cardiac side effect
Shortness of breath
Palpitation
Chest pain
Loss of consciousness
Paleness
Bleeding anywhere
76 (7.0)
93 (8.6)
56 (5.2)
7 (0.6)
35 (3.2)
5 (0.5)
21 (7.0)
10 (3.3)
11 (3.7)
0 (0.0)
6 (2.0)
0 (0.0)
0.017
0.010
0.023
0.362
0.311
0.167
Dizziness 157 (14.5) 27 (9.0) <0.001