FIG. 1.

Hyphal formation in the presence of fluconazole during growth and/or induction. Five isolates (isolates A1 to A5) (Table 1) were tested for hyphal formation. The isolates differed in their level of resistance (solid squares) as determined from the MICs. Isolates were tested for hyphal formation in the absence of fluconazole (open squares), with fluconazole added only during growth (open circles), with fluconazole added only during hyphal induction (diamonds), and with fluconazole added during both growth and induction (triangles). Cells were grown in YAD and were induced in M199. The fluconazole concentration used in this experiment was 10 μg/ml.