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. 2022 Mar 9;60(1):589–599. doi: 10.1080/13880209.2022.2039722

Figure 5.

Figure 5.

Overexpressed miR-29b-3p inhibited proliferation and promoted apoptosis in IL-1β-stimulated CHON-001 cells via down-regulating PTEN. (A, B) CHON-001 cells were divided into NC, PTEN, M, M + IL-1β, M + PTEN and M + IL-1β + PTEN groups. Colony numbers (A) and apoptosis rate (B) of CHON-001 cells were determined by colony formation and flow cytometry assays, respectively. MC: mimics control; M: miR-29b-3p mimics; NC: negative control. ***p < 0.001 vs. NC; #p < 0.05 or ###p < 0.001 vs. M; ∧∧∧p < 0.001 vs. M + IL-1β; ΔΔp < 0.01 or ΔΔΔp < 0.001 vs. M + PTEN. All measurements were performed at least three times. Data are presented as the means ± standard deviation (SD).