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. 2022 Mar 9;60(1):589–599. doi: 10.1080/13880209.2022.2039722

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© 2022 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 6. — Overexpressed miR-29b-3p regulated the expression of apoptosis-related proteins in IL-1β-stimulated CHON-001 cells via down-regulating PTEN. (A, B) CHON-001 cells was divided into NC, PTEN, M, M + IL-1β, M + PTEN and M + IL-1β + PTEN groups. The expression of apoptosis-related proteins (Bax, cleaved (C) caspase 3 and Bcl-2) were determined by Western blot. GAPDH was used as the internal reference control for PTEN. MC: mimics control; M: miR-29b-3p mimics; NC: negative control. **p < 0.01 or ***p < 0.001 vs. NC; ^###p < 0.001 vs. M; ^∧∧p < 0.01 or ^∧∧∧p < 0.001 vs. M + IL-1β; ^ΔΔΔp < 0.001 vs. M + PTEN. All measurements were performed at least three times. Data are presented as the means ± standard deviation (SD).