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. 2022 Feb 11;21(3):e13557. doi: 10.1111/acel.13557

FIGURE 1.

FIGURE 1

Senescence markers in APC from FDR and CTRL. (a) Flow cytometric detection of the SA‐β‐gal‐positive cells in APC from FDR (= 8) and CTRL (= 10) subjects available from our study cohort. Values are presented as percentage (%). The mRNA levels of CDKN1A (b) and LMNB1 (c) were measured by qPCR and normalized to RPL13A expression in APC from FDR (= 12) and CTRL (= 12) subjects. Values are presented as absolute units (AU). (a‐c) Data are shown as boxplots (min‐max) with all individual values. Significance was determined by Mann–Whitney test (a,c) or unpaired Student's t‐test (b). *p < 0.05, **p < 0.01, ***< 0.001 versus CTRL