Fig. 11.
Binding mode and structure of phenylethanoid glycosides (Forsythoside A-Acteoside) and pentacyclic triterpenoids (Betulinic acid-Glycyrrhizin) with in vitro demonstrated inhibitory activity in the active site of SARS-CoV-2 Mpro. Catalytic residues are colored (His41: green, Cys145: yellow), residues participating in hydrogen bonds are depicted as yellow dashes. The receptor-ligand complex was produced by docking simulations using the software YARASA Structure, replicating the binding mode represented in the relevant publication (Available in Table 3). (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)