TABLE 4.
MICs of β-lactams for E. coli strains and M. morganii 1 with different genotypes
| Strain | Relevant genotype | MIC (μg/ml)
|
|||
|---|---|---|---|---|---|
| Amoxicillin | Piperacillin | Ceftazidime | Cefotaxime | ||
| E. coli | |||||
| MC4100 | ampD+ ampE+ ampC | 4 | 0.5 | 0.5 | <0.06 |
| MC4100(pAC-1) | ampD+ ampE+ ampC+ ampR+ | 128 | 8 | 2 | 0.5 |
| MC4100(pAC-2) | ampD+ ampE+ ampC+ ampR | 512 | 32 | 16 | 2 |
| JRG582 | Δ(ampDE) | 1 | <0.5 | 0.5 | <0.06 |
| JRG582(pAC-1) | Δ(ampDE) ampC+ ampR+ | 256 | 8 | 8 | 1 |
| JRG582(pAC-1)(pNH5) | Δ(ampDE) ampC+ ampR+ ampD+ | 128 | 8 | 4 | 0.25 |
| M. morganii | |||||
| 1 | >512 | 32 | 4 | 4 | |
| 1(pNH5) | ampD+ | 16 | 2 | 0.5 | 0.12 |