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. 2022 Feb 24;13:818064. doi: 10.3389/fendo.2022.818064

Table 3.

List of genes of interests (GOI).

Gene symbol NN-Veh vs UN-RG-Veh UN-RG-Veh vs UN-RG-TU
Fold change P-value Fold change P-value
Saa3 7.60 0.0045 -10.88 0.0003
Ubd 4.73 0.0045 -5.86 0.0002
S100a8 3.17 0.0009 -5.19 <0.0001
Hpx 3.14 0.0003 -3.14 0.0007
Casp1 2.15 <0.0001 -1.96 <0.0001
Agt -1.94 0.0024 2.73 0.0013
Ptgs2 -1.8 0.0016 2.05 <0.0001

These seven genes were observed at least twice in four different gene ontologies (GO), i.e. 1) Inflammatory response, 2) Response to interferon-γ, 3) Regulation of cytokine production, and 4) Cellular response to interferon-β, and also met the conditions of a ≤−2 or ≥2 linear fold change and P-value <0.05. These four GO were commonly observed in two GO enrichment analyses (UN-RG-Veh vs NN-Veh and UN-RG-TU vs UN-RG-Veh) using data from the microarray analysis of epididymal adipose tissue.