Table 3.
Gene symbol | NN-Veh vs UN-RG-Veh | UN-RG-Veh vs UN-RG-TU | ||
---|---|---|---|---|
Fold change | P-value | Fold change | P-value | |
Saa3 | 7.60 | 0.0045 | -10.88 | 0.0003 |
Ubd | 4.73 | 0.0045 | -5.86 | 0.0002 |
S100a8 | 3.17 | 0.0009 | -5.19 | <0.0001 |
Hpx | 3.14 | 0.0003 | -3.14 | 0.0007 |
Casp1 | 2.15 | <0.0001 | -1.96 | <0.0001 |
Agt | -1.94 | 0.0024 | 2.73 | 0.0013 |
Ptgs2 | -1.8 | 0.0016 | 2.05 | <0.0001 |
These seven genes were observed at least twice in four different gene ontologies (GO), i.e. 1) Inflammatory response, 2) Response to interferon-γ, 3) Regulation of cytokine production, and 4) Cellular response to interferon-β, and also met the conditions of a ≤−2 or ≥2 linear fold change and P-value <0.05. These four GO were commonly observed in two GO enrichment analyses (UN-RG-Veh vs NN-Veh and UN-RG-TU vs UN-RG-Veh) using data from the microarray analysis of epididymal adipose tissue.