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. 2022 Mar 7;2022:1623181. doi: 10.1155/2022/1623181

Figure 2.

Figure 2

Basic mechanisms of MT organization during the differentiation of neurons into axons or dendrites. In axons, MTs display uniform polarity orientation with their plus-ends out. This array is essential to drive cargo transport through the proximal-end to the distal-end by kinesins, whereas in dendrites, MTs are mixed polarity with half of their minus-ends pointing to the soma, which allows dynein motors to selectively transport cargoes across this mixed MT arrays.