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Effect of pH on MIC of pexiganan when tested in nutrient broth
| Organism | No. of clinical isolates | Mean MIC (μg/ml)a
|
||||||
|---|---|---|---|---|---|---|---|---|
| pH 5.0 | pH 5.5 | pH 6.0 | pH 6.5 | pH 7.0 | pH 7.5 | pH 8.0 | ||
| Pseudomonas aeruginosa | 9 | 1.9 | 3.4 | 5.2 | 5.1 | 4.9 | 6.4 | 6.8 |
| Staphylococcus aureus | 11 | 7.7 | 14.7 | 10.7 | 6.9 | 5.4 | 4.3 | 3.6 |
| Staphylococcus epidermidis | 10 | NDb | 3.0 | 3.5 | 3.5 | 3.7 | 3.0 | 3.5 |
The geometric mean MICs for all isolates tested.
ND, the MIC was not determined.
