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. 2021 Oct 22;43:e2021090. doi: 10.4178/epih.e2021090

Table 2.

Subgroup analyses

Variables No. of studies HbA1c, SMD (95% CI) p-value Heterogeneity
Begg test
Egger test
I2 (%) p-value p-value p-value
All studies 12 -0.41 (-0.69, -0.13) 0.004 88 <0.001 0.410 0.519
Sample size
<100 8 -0.45 (-0.79, -0.11) 0.009 84 <0.001 0.620 0.413
≥100 4 -0.33 (-0.87, 0.20) 0.220 94 <0.001 0.496 0.988
Duration of intervention (mo)
≤6 6 -0.52 (-0.96, -0.07) 0.020 89 <0.001 0.188 0.108
>6 6 -0.32 (-0.71, 0.08) 0.120 90 <0.001 0.573 0.358
Baseline HbA1c (%)
<8.5 9 -0.42 (-0.77, -0.07) 0.020 91 <0.001 0.404 0.540
≥8.5 3 -0.36 (-0.62, -0.10) 0.006 11 0.320 0.601 0.692
Type of intervention delivery
Individual 0 - - - - - -
Group 6 -0.28 (-0.51, -0.06) 0.010 70 0.005 0.188 0.072
Combined 6 -0.53 (-1.07, 0.02) 0.060 92 <0.001 0.851 0.780
Frequency of contact
Low 2 -0.53 (-1.60, 0.54) 0.330 98 <0.001 0.317 <0.001
Moderate 3 -0.65 (-1.71, 0.40) 0.220 95 <0.001 0.601 0.494
High 7 -0.29 (-0.48, -0.10) 0.003 52 0.050 0.652 0.933

SMD, standard mean difference; HbA1c, glycated hemoglobin A1c; CI, confidence interval.