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. 2022 Mar 3;54(3):306–317. doi: 10.1038/s41588-022-01014-1

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Extended Data Fig. 9 — (A-H) Relative expression levels upon siRNA/ASO induced knockdown in primary fibroblasts of (A) Txnrd1 upon siRNA induced knockdown of 1700028I16Rik (n = 4 biologically independent samples), (B) Txnrd1 upon ASO induced knockdown of 1700028I16Rik (n = 4 biologically independent samples), (C) Tmc7 upon siRNA induced knockdown of B230311B06Rik, (D) Sox9 upon siRNA induced knockdown of 2610035D17Rik (n = 5 biologically independent samples), (E) Sox9 upon ASO induced knockdown of 2610035D17Rik (n = 5 biologically independent samples), (F) Fam78b upon siRNA induced knockdown of Gm16701, (G) Gsta4 upon siRNA induced knockdown of C920006O11Rik and (H) Hoxb9 and Hoxb13 upon siRNA induced knockdown of Gm53. A-H; measured by RT-qPCR, data presented as mean values + /- s.e.m., p-values represent a two-sided Student’s t-test.