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. 2022 Mar 1;13:813979. doi: 10.3389/fimmu.2022.813979

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Copyright © 2022 Chen, Zhu, Wang, Dong, Yu, Su, Huang, Huo and Wan

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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A20 expression of microglia decreased with glucose stimulation. (A) The heatmap of differentially expression gene profiles. (B) The top 10 enriched categories of molecular function in GO analysis. (C) The top 10 enriched categories of biological processes in GO analysis. (D) The top 10 enriched signal pathways of KEGG analysis. (E) The PPI network of differentially expressed mRNA. (F) The A20 expression at mRNA level decreased from 10 to 100 mM glucose treatment. (G) The A20 expression at protein levels decreased with 50 and 100 mM glucose treatment. Values are presented as the mean ± SD. ** indicates P < 0.01, and *** indicates P < 0.001.