TABLE 3.

Anti-SIV IgG responses in infant rhesus macaques following inoculation with SIV_mac055 or SIV_mac385

Animal group	Animal no.	SIVa	PMPAb	Anti-SIV IgG titer at the following times (wk) after virus inoculationc:
				0	2	3	4	6	7–8	10	12–13	14–16	18–21	30	39
A	29668	055	−	<100	<100	<100	<100	<100	<100	<100	400	<100d
	29669	055	−	<100	<100	<100	<100	<100	<100d
	29670	055	−	<100	<100	<100	<100	<100	<100d
B	29674	385	−	<100	<100	<100	<100	<100	<100	<100	<100d
	29675	385	−	<100	<100	<100	<100	<100	<100	<100d
	29729	385	−	<100	<100	<100	<100	<100	<100d
C	29283	055	+	<100	<100	<100	<100	<100	<100	<100	<100	<100	<100	<100	<100d
	29360	055	+	<100	<100	<100	<100	<100	<100	<100	<100	<100	<100d
	29419	055	+	<100	<100	<100	<100	<100	<100	<100	<100	<100	<100d
D	29276	385	+	<100	<100	100	1,600	25,600	25,600	25,600	25,600	25,600	102,400	102,400	102,400
	29278	385	+	<100	<100	100	1,600	25,600	25,600	25,600	25,600	6,400	25,600	102,400	102,400
	29279	385	+	<100	<100	<100	<100	6,400	6,400	6,400	25,600	25,600	102,400	102,400	102,400

^aAnimals were inoculated at birth with SIV_mac055 (055) or SIV_mac385 (385). 

^bGroups C and D were started on PMPA treatment 3 weeks after virus inoculation. 

^cAnti-SIV IgG titers at the indicated times after virus inoculation were determined by ELISA and are expressed as the reciprocal of the highest of fourfold dilutions (starting from a 1/100 dilution with two replicates per dilution) which gave a positive optical density above the cutoff value. Significant titers (titer, ≥400) are indicated in boldface. 

^dTime of death.