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. 2022 Mar 14;79(5):128. doi: 10.1007/s00284-022-02825-5

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — Principal component analysis of SCFA-supplemented cultures. a Bray–Curtis β diversity measures of control cultures compared to those supplemented with SCFAs. b Alpha diversity. Shannon diversity measures for control cultures compared to those observed in CDM supplemented with a single SCFA. c Modulatory effects of SCFAs. The average relative abundance of individual taxa in SCFA-supplemented cultures was compared to control cultures. Taxa displaying increased or decreased relative abundance (>fivefold) and the sum of these groups were summed and reported as altered. Taxa displaying changes < fivefold relative to control cultures were summed and reported as unaltered