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. 2021 Sep 28;49(4):1242–1253. doi: 10.1007/s00259-021-05493-y

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — FBP retention in the WM across the AD spectrum. (A) Voxel-wise analyses, adjusted for age, sex, and cortical FBP SUVR, contrasting SUVR levels in the WM of the different AD stages (the A- CN cohort was used as the reference). Statistical maps were thresholded using a p_FDR < 0.001. (B) Boxplots describing group-level adjusted SUVR in NAWM and WMH