Fig. 4.

Mean urinary excretion (µmol) over 24 h of sums of metabolites belonging to the same aglycone compound (3ʹOH-PVLs, sum of conjugates from the aglycone 5-(3′-hydroxyphenyl)-γ-valerolactone; 4ʹOH-PVLs, 5-(4ʹ-hydroxyphenyl)-γ-valerolactone; 3ʹ,4ʹdiOH-PVLs, 5-(3′,4′-dihydroxyphenyl)-γ-valerolactone; HPPs, 3-(hydroxyphenyl)propanoic acid), calculated both before and after cluster analysis (“Individual” and “Sums”, respectively). Clustering has been performed on the basis of: Final Consensus (first column), k-means (second column), expectation–maximization algorithm (third column), PC score forming 2 groups (fourth column), PC score forming 3 groups (fifth column). Different letters indicate statistically significant differences (p < 0.05) among groups 1 and 2 or 1, 2 and 3