Table 3.
CTEPH diagnosis confirmed, n = 9 (n, %) | CTEPH ruled out, n = 332 (n, %) | Univariate analysis (OR, 95%CI) | Sensitivity (%, 95%CI) | Specificity (%, 95%CI) | PPV (%, 95%CI) | NPV (%, 95%CI) | Positive likelihood ratio (95%CI) | Negative likelihood ratio (95%CI) | |
---|---|---|---|---|---|---|---|---|---|
Presence of ≥ 3 of 6 predictors of CTEPH | 4 (44) | 33 (10) | 7.2 (1.9–28) | 44 (14–79) | 90 (86–93) | 11 (5.2–21) | 98 (97–99) | 4.5 (2.0–9.9) | 0.62 (0.34–1.1) |
Overall judgment: CTEPH present | 8 (89) | 19 (5.7) | 132 (16–1109) | 89 (52–99.7) | 94 (91–97) | 30 (20–41) | 99.7 (98–99.9) | 16 (9.5–25) | 0.12 (0.0–0.8) |
Abbreviations: CTEPH, chronic thromboembolic pulmonary hypertension; OR, odds ratio; 95%CI, 95% confidence interval; PPV, positive predictive value; NPV, negative predictive value