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. 2021 Dec 2;32(4):2178–2187. doi: 10.1007/s00330-021-08364-0

Table 3.

Results of the assessment of radiological signs of CTEPH in patients ultimately diagnosed with CTEPH versus those in whom CTEPH was ruled out after 2-year follow-up

CTEPH diagnosis confirmed, n = 9 (n, %) CTEPH ruled out, n = 332 (n, %) Univariate analysis (OR, 95%CI) Sensitivity (%, 95%CI) Specificity (%, 95%CI) PPV (%, 95%CI) NPV (%, 95%CI) Positive likelihood ratio (95%CI) Negative likelihood ratio (95%CI)
Presence of ≥ 3 of 6 predictors of CTEPH 4 (44) 33 (10) 7.2 (1.9–28) 44 (14–79) 90 (86–93) 11 (5.2–21) 98 (97–99) 4.5 (2.0–9.9) 0.62 (0.34–1.1)
Overall judgment: CTEPH present 8 (89) 19 (5.7) 132 (16–1109) 89 (52–99.7) 94 (91–97) 30 (20–41) 99.7 (98–99.9) 16 (9.5–25) 0.12 (0.0–0.8)

Abbreviations: CTEPH, chronic thromboembolic pulmonary hypertension; OR, odds ratio; 95%CI, 95% confidence interval; PPV, positive predictive value; NPV, negative predictive value