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. 2022 Mar 14;13(3):234. doi: 10.1038/s41419-022-04681-4

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — Overlapped differentially expressed (A) and methylated (B) genes following P. aeruginosa infection for 2, 4 and 6 h. C Overall m⁶A distribution on cellular mRNA and lncRNA at different time points following P. aeruginosa infection. D Overlapped differentially expressed genes with hypermethylation and hypomethylation following P. aeruginosa infection for 2, 4 and 6 h. E Correlation of mRNA expression level and m⁶A level for differentially expressed and methylated genes at 2, 4 and 6 h P. aeruginosa post-infection. The regression lines are marked in “blue”. Innate immune related genes are marked with “red dots”.