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. 2022 Mar 14;13(3):236. doi: 10.1038/s41419-022-04682-3

Fig. 1. RUBCN-deficient mice are hypersensitive to kidney ischemia-reperfusion injury (IRI).

Fig. 1

Indicated numbers of 8–12-weeks-old male mice were either subjected to sham surgery or underwent bilateral kidney IRI. 48 h following the onset of reperfusion, serum creatinine (A) and serum urea (B) concentrations were measured and mice were sacrificed. Kidneys were stained for periodic acid Schiff (PAS) and two representative magnifications are demonstrated in C and quantified according to an established tubular damage score in D. Statistical analysis was performed using Student’s t-test (p-values are indicated for each experiment).