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. 2022 Mar 14;13:1299. doi: 10.1038/s41467-022-28931-3

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — a Side view of the atomic model of apo hMPV F variant (DS-CavEs2) in a prefusion conformation. The model (red ribbon) is superimposed with a previously determined hMPV F structure (white ribbon, PDB ID: 5WB0). The side chains of the introduced substitutions are highlighted as sticks. Each inset corresponds to the regions where the superimposition is performed. b Representative negative stain EM 2D class averages of DS-CavEs2 complexed with MPE8 Fab.