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. 2022 Mar 14;12:101. doi: 10.1038/s41398-022-01847-8

Table 2.

Week 8 symptom improvement in the GEN and TAU treatment arms, according to HAM-D17.

	Symptom improvement
	Mean percentage change			Mean change
	Estimate,% (SE)^a	Difference	p-value	Estimate (SE)^b	Difference	p-value
Per Protocol
GEN (N = 65)	24.41 (3.85)	1.82	0.738	5.23 (0.74)	0.13	0.901
TAU (N = 69)	22.60 (3.80)	1.82	0.738	5.10 (0.73)	0.13	0.901
Intent-to-Treat
GEN (N = 106)	22.42 (3.42)	4.61	0.350	4.70 (0.57)	0.672	0.414
TAU (N = 97)	17.80 (3.55)	4.61	0.350	4.03 (0.59)	0.672	0.414

^aMean percent change in HAM-D17 score from baseline to week 8.

^bMean absolute change in HAM-D17 score from baseline to week 8.