FIG. 1.

Reversible phenotypic switching of C. lusitaniae 7227. Single colonies were diluted and subcultured on SD agar without AmB (−AmB) or with AmB at 0.15 μg/ml (+AmB). Representative plates inoculated with either 0.2 or 100 μl of the initial cell suspension are shown. The isolates are labeled as follows: designations that include “S” indicates isolates that are derived from a susceptible lineage; “R” indicates a resistant lineage; “SR” indicates isolates that switched from a susceptible to a resistant phenotype; and “RS” indicates isolates that switched from a resistant to a susceptible phenotype. Numbers following these labels indicate clonal lineages.