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. 2022 Mar 8;15:395–402. doi: 10.2147/CCID.S266036

Table 1.

Summary of Key Efficacy Data of Apremilast in Plaque Psoriasis: Results from Phase 3 ESTEEM Trials

Study Treatment Arm Number of Patients PASI-75 Response sPGA Response
ESTEEM 1 Apremilast 30 mg BID 562 186 (33.1%) 122 (21.7%)
Placebo 282 15 (5.3%) 11 (3.9%)
Total 844
ESTEEM 2 Apremilast 30 mg BID 274 79 (28.8%) 56 (20.4%)
Placebo 137 16 (5.8%) 12 (4.4%)
Total 411

Abbreviation: BID, twice daily.