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. 2022 Mar 1;13:838790. doi: 10.3389/fmicb.2022.838790

TABLE 8.

Deduced amino acid sequences of PBP2b in 300 S. pneumoniae isolates.

PBP2b group n Percent (%) Number of substitution sites Substitution rate (%) 3 3 3 3 3 3 3 3 3 3 3 3 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6
1 1 2 2 3 5 6 6 6 6 7 8 0 1 1 1 1 2 2 2 2 2 2 3 3 3 3 3 3 4 4 5 6 6 7 7 7 8 8 8 9 9 0 0 0 0 1 1 1 2 3 3 4 4 5 5 5 6 6 6 6 6 6 7 7 7 8 8 8 8 9 9 9 0 0 1 2 2 2 2 4 4 5 6 6 7 7 7
5 9 1 2 3 7 1 4 6 9 2 3 6 1 2 4 9 2 4 6 7 8 9 0 1 2 7 8 9 6 9 5 7 9 0 3 6 0 3 9 0 7 2 3 6 7 2 0 6 0 3 8 2 5 2 5 6 1 5 6 7 8 9 1 4 8 1 2 3 5 2 5 7 6 9 9 4 5 8 7 0 1 9 0 4 4 5 6
A S D A E S I D K E P V Q Q S V A N Ins T Q A Y G S F V Q A T V L G S N S E S G T A D F V E S Y A A F A N V R G D K D Q L Q P T M V D M S I H A T G N L A A D Q T S D N G S Q K Y
2B 01 52 17.3 0 0.0
2B 02 3 1.0 1 0.3 I
2B 03 3 1.0 1 0.3 P
2B 04 27 9.0 1 0.3 E
2B 05 1 0.3 1 0.3 N
2B 06 4 1.3 1 0.3 I
2B 07 1 0.3 1 0.3 S
2B 08 2 0.7 1 0.3 T
2B 09 4 1.3 1 0.3 N
2B 10 3 1.0 2 0.5 D E
2B 11 4 1.3 2 0.5 D E
2B 12 1 0.3 2 0.5 D I
2B 13 1 0.3 2 0.5 E E
2B 14 1 0.3 6 1.6 G L K G S D
2B 15 1 0.3 9 2.4 A G A D N F D V E
2B 16 1 0.3 12 3.2 E A I L N G A A S I N D
2B 17 7 2.3 12 3.2 G L P K E A I G S F D I
2B 18 1 0.3 12 3.2 P Y K L E A I T G A A D
2B 19 1 0.3 12 3.2 G P Y K L E A I T G A A
2B 20 43 14.3 13 3.5 G P Y K L E A I T G A A S
2B 21 1 0.3 13 3.5 P Y K L E T A I T G A A D
2B 22 6 2.0 13 3.5 E A I L N G A A S I N D V
2B 23 1 0.3 13 3.5 G A F S R P M A G S I D V
2B 24 10 3.3 14 3.8 G L P Y K L E A I T G A A D -
2B 25 1 0.3 14 3.8 G P P Y K L E A I T G A A S -
2B 26 22 7.3 15 4.0 G N Q P Y K L E A I T G A A D -
2B 27 4 1.3 15 4.0 G P Y K L E A I T G A A D D E
2B 28 2 0.7 22 5.9 G L N Q P Y K L E A G S D D A E G E N N Q H
2B 29 2 0.7 45 12.1 G L N Q P Y K L E A I T G A A D D L H D E A I D T K I E A S P D T G G E N T E K N A N Q H
2B 30 1 0.3 17 4.6 G P Y K L E A I T G A A D A G E N
2B 31 2 0.7 17 4.6 P Y K L E A I T G A A I N F D V E
2B 32 1 0.3 17 4.6 A F S V P A G S I D G E N N Q H
2B 33 2 0.7 18 4.8 A F S V P A G S I N F D – - V A G E N
2B 34 2 0.7 18 4.8 G L P Y K L E A I T G A A D A G E N
2B 35 5 1.7 18 4.8 S S T A N E D P Y K L E A I T G A A -
2B 36 2 0.7 18 4.8 L P Y K L E A I T G A A S D A G E N
2B 37 1 0.3 38 10.2 P E A I L N G A A S I N G I H E Q N S V E S K I E V Q G A S E G E N N Q H
2B 38 1 0.3 19 5.1 L H P Y K L E A I T G A A S D – - - A G E N
2B 39 1 0.3 32 8.6 G L D P Y K L E A I T G A A D E A I D T K I E A S E G E N N Q H
2B 40 1 0.3 32 8.6 G L I P Y K L E A I T G A A Y D P D T G G E N T E K N A N Q H
2B 41 1 0.3 37 9.9 G L T F K S I G S L T D E A I D T K I E A P D T G G D S T E K N A N Q H
2B 42 1 0.3 38 10.2 G P Y K L E A I T G A A D E A I D T K I E A P D T G G E N T E K N A N Q H
2B 43 27 9.0 40 10.8 G L D P Y K L E A I T G A A D E A I D T K I E A P D T G G E D T E K N A N Q H
2B 44 40 13.3 40 10.8 G L N P Y K L E A I T G A A D E A I D T K I E A P D T G G E N T E K N A N Q H
2B 45 1 0.3 9 2.4 L S YTW S G S D V E
2B 46 1 0.3 8 2.2 G L S YIW S G S D -