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. 2020 Oct 6;31(4):459–476. doi: 10.1093/glycob/cwaa093

Table II.

Secondary structure of mammalian fucosylated epitopes

graphic file with name cwaa093fx7.jpg

Distal epitopes can be present either in the terminal glycan chain or in the middle of the polylactosamine extension. The synthesis of Lewis (Le) antigens is catalyzed by FucT-1, FucT-2, FucT-3, FucT-4, Fuct-5, FucT-6, FucT-7 and FucT-9. Biosynthesis of ABO groups is catalyzed by FucT-1 and FucT-2. Addition of CF epitope with the specific linkage α(1,6) is catalyzed by the unique FucT-8 enzyme. Structures are illustrated according to the SNFG notation: Inline graphic Gal (Galactose); Inline graphic Man (Mannose); Inline graphic Fuc (Fucose); Inline graphic GlcNAc (N-Acetylglucosamine); Inline graphic GalNAc (N-Acetylgalactosamine); Inline graphic Neu5Ac (N-Acetylneuraminic acid).