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Pooled odds ratio for successful reperfusion (mTICI ≥2b) at the end the endovascular procedure in ‘mothership’ anterior circulation large vessel occlusion stroke patients treated with MT alone vs. IVT plus MT within 4.5 hrs of symptom onset (unadjusted pooled OR, random-effects meta-analysis). Abbreviations: dMT: direct mechanical thrombectomy (MT alone); IVT: intravenous thrombolysis with alteplase; MT: mechanical thrombectomy.
