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Pooled odds ratio for symptomatic intracerebral hemorrhage (sICH) in ‘mothership’ anterior circulation large vessel occlusion stroke patients treated with MT alone vs. IVT plus MT within 4.5 hrs of symptom onset (unadjusted pooled OR, random-effects meta-analysis). The definition of sICH varied across studies (see Table 2 for details). Abbreviations: dMT: direct mechanical thrombectomy (MT alone); IVT: intravenous thrombolysis with alteplase; MT: mechanical thrombectomy.
