Table 1.
Patient characteristics of all adult ICHs from 2007–2009 and 2017–2019.
| N | All ICHs 2007–2009 | All ICHs 2017–2019 | p value a | |
|---|---|---|---|---|
| N | 1174 | 652 | 522 | |
| Sex, men (%) | 339 (52.0) | 262 (50.2) | .539 | |
| Age, median in y [IQR] | 76.3 (66.6–83.0) | 75.0 (65.9–82.7) | .372 | |
| OAC-related ICH (%) | 168 (25.8) | 121 (23.2) | .307 | |
| VKA-related ICH (%) | 168 (25.8) | 70 (13.4) | <.001 | |
| DOAC-related | 0 | 51 | <.001 | |
| Prior ICH (%) | 1168 | 65 (10.0) | 56 (10.8) | .695 |
| Antiplatelet therapy (%) | 1163 | 228 (35.5) | 146 (28.0) | .007 |
| Hypertension (%) | 1152 | 431 (68.3) | 348 (66.8) | .586 |
| Diabetes mellitus (%) | 1157 | 110 (17.3) | 100 (19.2) | .405 |
| Hypercholesterolemia (%) | 1148 | 260 (41.5) | 234 (44.8) | .262 |
| Current smoking (%) | 835 | 113 (27.4) | 79 (18.7) | .003 |
| GCS-score ≤ 8 (%) | 1173 | 134 (20.6) | 75 (14.4) | .006 |
| ICH location (%) | ||||
| Lobar | 290 (44.5) | 240 (46.0) | ||
| Deep lobar | 272 (41.7) | 222 (42.5) | .027 | |
| Infratentorial | 90 (13.8) | 55 (10.5) | ||
| Multifocal | 0 | 5 (1.0) | ||
| ICH volume, median in cc [IQR] | 1165 | 15.6 [4.3–44.5] | 11.9 [3.5–33.0] | .023 |
| Intraventricular extension (%) | 286 (43.9) | 172 (33.0) | <.001 | |
| Hospital mortality (%) | 256 (39.3) | 160 (30.7) | .002 |
ap value for the difference between All ICHs 2007–2009 and All ICHs 2017–2019.
Abbreviations: ICH - intracerebral hemorrhage; N - number of ICH cases; y - years; IQR - interquartile range; OAC-related ICH - oral anticoagulant-related intracerebral hemorrhage; VKA-related ICH - Vitamin K-related intracerebral hemorrhage; DOAC-related ICH - Direct Oral Anticoagulant-related intracerebral hemorrhage, GCS-score - Glasgow Coma Scale-score; cc - cubic centimeter.