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. 2022 Feb 6;11(6):1454–1464. doi: 10.1002/cam4.4569

FIGURE 4.

FIGURE 4

NCL knockdown induces apoptosis by inhibiting the PI3K/AKT pathway. (A) A heat map of differentially expressed genes in all samples. Rows represent genes, whereas columns represent samples. (B) Pathway enrichment analysis of transcriptome profiling. (C) Enrichment of differentially expressed genes in the PI3K/AKT pathway. (D) Diagram showing the fold‐change of several typical genes using RT‐PCR. **p < 0.01, versus the sh‐NT‐HeLa group. NCL, nucleolin