Table 4.
Individual Participant Mosquito Transmission Results
| Participant No. | Mosquito Infection Rate, Mosquitoes With Oocysts, No./Mosquitoes Tested, No (%) | |||
|---|---|---|---|---|
| d 8 After Inoculation | d 10 After Inoculationa | |||
| DFA | DMFA | DFA | DMFA | |
| 1 | 0/30 (0%) | 0/50 (0) | 0/19 (0) | 0/50 (0) |
| 2 | 0/29 (0) | 0/50 (0) | 0/29 (0) | 1/50 (2.0) |
| 3 | 0/30 (0) | 0/50 (0) | 0/30 (0) | 0/50 (0) |
| 4 | 0/30 (0) | 0/50 (0) | 1/30 (3.3) | NP |
| 5 | 0/29 (0) | 0/50 (0) | 2/30 (6.7) | 1/50 (2.0) |
| 6 | 0/28 (0) | 0/50 (0) | 19/30 (63.3) | 6/50 (12.0) |
| 7 | 0/30 (0) | 0/50 (0) | 2/30 (6.7) | 0/50 (0) |
| 8 | 0/30 (0) | 0/50 (0) | 0/30 (0) | 1/50 (2.0) |
Abbreviations: DFA, direct feeding assay; DMFA, direct membrane feeding assay; NP, not performed.
a Mosquito transmission assays on day 10 were performed immediately before artefenomel dosing.