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. 2022 Mar 1;12:782730. doi: 10.3389/fonc.2022.782730

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Copyright © 2022 Shi, Yang, Kong, Qiu, Lu, Liu, Liu and Du

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Kaplan–Meier analysis of patient significant factors in the multivariate analyses and outcomes of patients. PFS was analyzed according to the optimal CA19-9 response (A) and chemotherapy cycles (B). OS was analyzed according to the optimal CA19-9 response (C) and chemotherapy cycles (D). PFS, progression-free survival; OS, overall survival. Optimal CA19-9 response: Normalization and/or ≥50% decline compared with baseline.