Table 2.
Bactericidal Effect of BPO on C. acnes
| Contact Time (min) | Bactericidal Isolates (n (%)) | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1.25% | 2.5% | 5% | 10% | |||||||||
| Total (n=30) | R† (n=17) | NR‡ (n=13) | Total (n=30) | R† (n=17) | NR‡ (n=13) | Total (n=30) | R† (n=17) | NR‡ (n=13) | Total (n=30) | R† (n=17) | NR‡ (n=13) | |
| 0.5 | 20 (66.7%) | 9 (53%) | 11 (84.6%) | 28 (93.4%) | 15 (88.2%) | 13 (100%) | 30 (100%) | 30 (100%) | 30 (100%) | 30 (100%) | 30 (100%) | 13 (100%) |
| 1 | 21 (70%) | 10 (58.8%) | 11 (84.6%) | 28 (93.4%) | 15 (88.2%) | 13 (100%) | 30 (100%) | 30 (100%) | 30 (100%) | 30 (100%) | 30 (100%) | 13 (100%) |
| 5 | 21 (70%) | 10 (58.8%) | 11 (84.6%) | 29 (96.7%) | 16 (94%) | 13 (100%) | 30 (100%) | 30 (100%) | 30 (100%) | 30 (100%) | 30 (100%) | 13 (100%) |
| 10 | 22 (73.3%) | 10 (58.8%) | 12 (92.3%) | 29 (96.7%) | 16 (94%) | 13 (100%) | 30 (100%) | 30 (100%) | 30 (100%) | 30 (100%) | 30 (100%) | 13 (100%) |
| 15 | 24 (80%) | 12 (70%) | 12 (92.3%) | 30 (100%) | 17 (100%) | 13 (100%) | 30 (100%) | 30 (100%) | 30 (100%) | 30 (100%) | 30 (100%) | 13 (100%) |
| 30 | 26 (86.7%) | 14 (82.3%) | 12 (92.3%) | 30 (100%) | 17 (100%) | 13 (100%) | 30 (100%) | 30 (100%) | 30 (100%) | 30 (100%) | 30 (100%) | 13 (100%) |
| 60 | 30 (100%) | 17 (100%) | 13 (100%) | 30 (100%) | 17 (100%) | 13 (100%) | 30 (100%) | 30 (100%) | 30 (100%) | 30 (100%) | 30 (100%) | 13 (100%) |
Notes: Bactericidal effect on 
≤ 80% of isolates 
80–89% of isolates 
90–99% of isolates 
100% isolates. †Antibiotic-resistant isolates. ‡Antibiotic-susceptible isolates.
Abbreviations: BPO, benzoyl peroxide; MIC, minimal inhibition concentration; DMSO, dimethyl sulfoxide.