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. 2021 Nov 28;29(4):643–651. doi: 10.1093/jamia/ocab264

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© The Author(s) 2021. Published by Oxford University Press on behalf of the American Medical Informatics Association.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 1. — The Biobank Portal architecture is based on Informatics for Integrating Biology and the Bedside (i2b2). Investigators access data through the webclient which interacts with the i2b2 application server using application programming interfaces (APIs). Most data are ingested into the data repository directly, but other data are accessed using external APIs at query time. PM: Project management cell; ONT: Ontology cell; CRC: Data repository cell; OMOP: Observational medical outcome partnership; CDM: common data model; VCF: variant call format; ETL: extract-transform-load.