Table 1.

Guiding Principles of the LACDHS Research Oversight Board (complete document Supplementary Appendix S1)

Support meaningful, proportionate, and impactful healthcare research that aims to achieve the LACDHS mission	Streamline and facilitate research approvals	Enhance accuracy, availability, and management of data for research	Set out a framework to guide oversight and the decision-making process	Promote institutional capacity and external collaboration for research
That is, support effectiveness research, which directly impacts the LACDHS patient population That is, support efficiencies that align project review, approval, and oversight processes	Streamline the IRB process with other regulatory and LACDHS oversight approvals Harmonize IRB and compliance processes across the network of Los Angeles County institutions	Subsume the rules for access and use of research data under the LACDHS Business Intelligence governance model	A guidance for resource and research planning (refer to Table 2) Discussions the framework will generate are understood to be complex and the Research Oversight Board is empowered to establish precedence	Facilitate changes to LACDHS operational practices from within the office of the Chief Medical Officer and from the Research Oversight Board Facilitate a meaningful and effective mentorship model for opportunity creation Facilitate partnerships with regional and national networks

IRB: Institutional Review Board.