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Integrative role of ketone bodies in the nervous system. Mechanisms supporting the pleiotropic effects of ketone bodies or a ketogenic diet in the nervous system still require elucidation. However, effects on feeding behavior, energy expenditure, mood and behavior, and neuroprotection have all been observed. Abbreviations: Glc, glucose; KB, ketone body; TCA, tricarboxylic acid. Figure adapted from images created with BioRender.com.
