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Coronaviridae (CoV) pre-TMD regions are enriched in aromatic residues as compared to other viruses. The panels show (a) all aromatic residues, (b) W, (c) Y and (d) F. p-values (Wilcoxon test): (a) p < 0.05, (b) and (c) p < 0.001, (d) p < 0.08.
