Figure 4. Plant ER-phagy receptors.
(A–C) Diagrams depicting the plant ER-phagy receptors identified to date: Arabidopsis Sec62 (A), maize Rtn1/2 (B), and Arabidopsis C53 (C). The interacting proteins or complexes are also illustrated. C53 is in a heteromeric receptor complex with UFL1 and DDRGK1. The strength of the interaction between C53 and Atg8 is enhanced by ER stress induced by tunicamycin, while the interaction between C53 and UMF1 is reduced in these conditions. See main text for details. Diagrams not in scale. Orientation of the ER-phagy receptors is presented with respect to the ER membrane, ER lumen, and cytosol. N and C, N and C terminus of the proteins.